The art and science of pharmaceutical innovation meet at our recently expanded 840,000+ square-foot facilities in West Columbia, South Carolina.

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Nephron is the world's largest blow-fill-seal (BFS) manufacturing company by total capacity.

We efficiently produce a range of products using BFS technology, and we've expanded our footprint to boast over 840,000 square feet of space.

Innovating for the Future

We designed our LEED-certified facilities in South Carolina to lead the world in blow-fill-seal (BFS) manufacturing. This technology forms, fills, and seals vials in one continuous process without human interaction. For decades, we have specialized in producing generic respiratory medications using BFS. Our West Columbia facilities have been designed to produce several billion doses annually of inhalation products and other sterile compounded medications.

Nephron Pharmaceuticals earned the 2017 Global Facility of the Year Honorable Mention by the International Society for Pharmaceutical Engineering.

The ISPE established the Facility of the Year Awards (FOYA) to recognize companies that utilize new and innovative technologies. The FOYA program provides a platform for manufacturers in the healthcare industry to showcase accomplishments and cutting-edge approaches.

Learn More About ISPE

Automation Drives Quality and Efficiency

At our award-winning facilities, we run a completely automated manufacturing, packaging, and distribution process. This maximizes production efficiency and minimizes the risk of human error and contamination. After our products are formed using blow-fill-seal (BFS) technology, a fleet of unmanned forklifts, or laser guided vehicles, move the finished medicines to our warehouse. Our automated packaging system barcodes all medication and places them into cartons for shipping to end users.

Our high-volume and redundant utility systems maximize our production capability. Over the last eight years, we have distributed more than one billion doses of respiratory medicine annually.


Nephron's industry-leading manufacturing plant in West Columbia, S.C. promotes a positive environmental image by incorporating green building practices into the facilities. By taking a sustainable approach to manufacturing, we are able to leave a lasting impact on the environment, while also enjoying energy and cost savings.

Our facilities were designed to combat indoor air quality issues, and is equipped with energy efficient lighting and ventilation systems that are adequate for all necessary tasks. The building uses at least 30% less water and 10% less energy than the U.S. Green Building Council (USGBC) baseline for buildings of similar size and occupation.

Recycle bins are located in each department throughout the facilities, and employees are encouraged to separate recyclables from trash. Recycling programs are in place for paper, plastics, aluminum, glass, cardboard, metal, batteries, electronics, and pallets/wood. In addition, several spaces in the employee parking lots are reserved for energy efficient vehicles as part of our LEED certification.

Committed to Helping Patients

Patients deserve safe and effective medicines, and we play a key role in making that a reality. By using industry-leading technology at every phase of the manufacturing process, we are able to meet and exceed safety and quality standards. We have been delivering high-quality products to patients for nearly 30 years. We are committed to constantly exploring ways to improve our facilities, our people, and our processes, with the ultimate goal of helping more patients.

Nephron Earns LEED Silver Certification

Nephron Pharmaceuticals Corporation is a LEED Silver Certification member, issued by the U.S. Green Building Council (USGBC). LEED, or Leadership in Energy and Environmental Design, is the most widely used green building rating system in the world, and provides a framework to create healthy, highly efficient and cost-saving green buildings. LEED certification is a globally recognized symbol of sustainability achievement. At Nephron, we are proud to be an industry leader, supporting the ongoing development of a prosperous and sustainable future.

Investments in pharmaceutical innovation are investments in improving patient outcomes. We are proud to bring affordable, life-saving products to patients every day.


We ship 1,000,000,000+ doses of medication a year.

Our roof is the size of 4.5 football fields

Over 500,000 square feet of drywall were used to build our walls

6 miles of PVC were installed just for the irrigation system

8 acres of sod were used for our landscaping

3,300 trucks of concrete were used to build Nephron (the equivalent of 33,000 cubic yards)